@article { ISI:000310863400012,
	title = {Carbohydrate-derived conformationally restricted bicyclic dipeptides as potential hetero foldamer building blocks},
	journal = {Tetrahedron-Asymmetry},
	volume = {23},
	number = {18-19},
	year = {2012},
	month = {OCT},
	pages = {1400-1404},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>Starting from carbohydrate precursors, hetero foldamer building blocks featuring diverse amino acid side chains and stereochemistry have been accessed via a multi-step synthetic protocol. These conformationally restricted bicyclic dipeptide building blocks are characterized by a constrained beta-lactam ring fused with a pyrrolidine ring carrying a hydroxyethylamine isostere (HEA) on the backbone. These building blocks offer the possibility of developing foldamers with interesting structural architectures, conspicuously different from those classically observed. Furthermore, such hetero-building blocks have the potential to augment the conformational space available for foldamer design with diverse backbone conformations and structural architectures. (C) 2012 Elsevier Ltd. All rights reserved.</p>},
	issn = {0957-4166},
	doi = {10.1016/j.tetasy.2012.08.007},
	author = {Ramesh, Veera V. E. and Puranik, Vedavati G. and Sanjayan, Gangadhar J.}
}
