@article { ISI:000322949600001,
	title = {Chitinolytic enzymes: an appraisal as a product of commercial potential},
	journal = {Biotechnology Progress},
	volume = {29},
	number = {4},
	year = {2013},
	month = {JUL},
	pages = {833-846},
	publisher = {WILEY-BLACKWELL},
	address = {111 RIVER ST, HOBOKEN 07030-5774, NJ USA},
	abstract = {<p>Chitin, its deacetylated form, chitosan and chitinolytic enzymes viz. endo-chitinase, N-acetylglucosaminidase, chitosanase, chitin deacetylase (CDA) are gaining importance for their biotechnological applications. Presently, chitin degrading enzymes constitute high-cost low-volume products in human health care and associated research. Indeed chitinases and CDA-chitosanase complex possesss tremendous potential in agriculture to control plant pathogenic fungi and insects. The success in exploring chitinases especially for agriculture, i.e. as a high-volume low-cost product, depends on the availability of highly active preparations with a reasonable cost. Therefore, a reconsideration in terms of understanding the roles of chitinolytic enzymes in applications, e.g. host-pathogen interaction for biocontrol, different mechanisms of chitin degradation, and identification of new enzymes with varying specificities, may make them more useful in a variety of commercial processes in the near future. The possible issues and challenges encountered in the translation of proof of concept into a commercial product will be appraised in this review. (c) 2013 American Institute of Chemical Engineers Biotechnol. Prog., 29:833-846, 2013</p>},
	keywords = {chitin deacetylase, chitinase, chitosanase, high-cost low-volume product, high-volume low-cost product},
	issn = {8756-7938},
	doi = {10.1002/btpr.1732},
	author = {Chavan, S. B. and Deshpande, Mukund V.}
}
