@article { ISI:000343067700009,
	title = {Experimental determination of the electrostatic nature of carbonyl hydrogen-bonding interactions using IR-NMR correlations},
	journal = {Journal of Physical Chemical Letters},
	volume = {5},
	number = {18},
	year = {2014},
	month = {AUG},
	pages = {3211-3215},
	publisher = {AMER CHEMICAL SOC},
	type = {Article},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>Hydrogen-bonding plays a fundamental role in the structure, function, and dynamics of various chemical and biological systems. Understanding the physical nature of interactions and the role of electrostatics in hydrogen-bonding has been the focus of several theoretical and computational research. We present an experimental approach involving IR-C-13 NMR correlations to determine the electrostatic nature of carbonyl hydrogen-bonding interactions. This report provides a direct experimental evidence of the classical nature of hydrogen-bonding interaction in carbonyls, independent of any theoretical approximation. These results have important implications in chemistry and biology and can be applied to probe the reaction mechanisms involving carbonyl activation/stabilization by hydrogen bonds using spectroscopic techniques.</p>},
	issn = {1948-7185},
	doi = {10.1021/jz501613p},
	author = {Kashid, Somnath M. and Bagchi, Sayan}
}
