@article { ISI:000365307400018,
	title = {Chemoenzymatic collective synthesis of optically active hydroxyl(methyl)tetrahydronaphthalene-based bioactive terpenoids},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {13},
	number = {46},
	year = {2015},
	month = {SEP},
	pages = {11331-11340},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>Starting from succinic anhydride and 2-methylanisole, a chemoenzymatic collective formal/total synthesis of several optically active tetrahydronaphthalene based bioactive natural products has been presented via advanced level common precursors; the natural product and antipode (-)/(+)-aristelegone B. Regioselective benzylic oxidations, stereoselective introduction of hydroxyl groups at the alpha-position of ketone moiety in syn-orientation, efficient enzymatic resolutions with high enantiomeric purity, stereoselective reductions, samarium iodide induced deoxygenations and tandem acylation-Wittig reactions without racemization and/or eliminative aromatization were the key features. An attempted diastereo-selective synthesis of (+/-)-vallapin has also been described.</p>},
	issn = {1477-0520},
	doi = {10.1039/c5ob01740h},
	author = {Batwal, Ramesh U. and N. P. Argade}
}
