@article { ISI:000366864700011,
	title = {Employing carboxylic acids in aryne multicomponent coupling triggered by aziridines/azetidines},
	journal = {Organic Chemistry Frontiers},
	volume = {3},
	number = {1},
	year = {2016},
	month = {NOV},
	pages = {71-76},
	publisher = {CHINESE CHEMICAL SOC},
	address = {PO BOX 1-18, NANKANG, TAIPEI 115, TAIWAN},
	abstract = {<p>The transition-metal-free aryne multicomponent coupling (MCC) involving carboxylic acids initiated by aziridines/azetidines has been reported. The use of aziridines as nucleophiles afforded N-aryl beta-amino alcohol derivatives and the application of azetidines as nucleophilic triggers furnished N-aryl gamma-amino alcohol derivatives in moderate to good yields. These reactions proceed under mild conditions and result in the formation of a new carbon-nitrogen bond and a new carbon-oxygen bond. The utility of carboxylic acids in aryne MCCs has been demonstrated, and the synthetic potential of phenols as acid surrogates in the present aryne MCCs has been realized.</p>},
	issn = {2052-4129},
	doi = {10.1039/c5qo00328h},
	author = {Roy, Tony and Bhojgude, Sachin Suresh and Kaicharla, Trinadh and Thangaraj, Manikandan and Garai, Bikash and Biju, Akkattu T.}
}
