@article { ISI:000368207600006,
	title = {Formal total synthesis of anti-helicobacter pylori agent (+)-spirolaxine methyl ether},
	journal = {Tetrahedron Letters},
	volume = {57},
	number = {1},
	year = {2016},
	month = {JAN},
	pages = {25-28},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A convergent, formal enantioselective synthesis of anti-Helicobacter pylori agent, (+)-spirolaxine methyl ether 2 has been achieved in high enantiomeric purity starting from commercially available 1,5-pentanediol. The strategy mainly comprises of the Noyori{\textquoteright}s asymmetric reduction and Brown allylation/Cu-catalyzed lactonization as the key step for the construction of key chiral intermediates, spiroketal 3 and phthalide fragment 4. (C) 2015 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Brown allylation, Cu-catalyzed lactonization, Noyori{\textquoteright}s asymmetric reduction, Phthalide, Spiroketal},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2015.11.047},
	author = {Gadakh, Sunita K. and Sudalai, Arumugam}
}
