@article { ISI:000371344600012,
	title = {Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents},
	journal = {Bioorganic \& Medicinal Chemistry Letters},
	volume = {26},
	number = {7},
	year = {2016},
	month = {APR},
	pages = {1704-1708},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>We have developed, highly efficient, one-pot, solvent-free, [Et3NH][HSO4] catalyzed multicomponent reaction protocol for the synthesis of 1,3-thiazolidin-4-ones in excellent yields. For the first time, the 1,3-thiazolidin-4-ones were evaluated in vitro for their antimycobacterial activity against Mycobacterium tuberculosis dormant MTB H37Ra and Mycobacterium bovis BCG strains. Among the synthesized basic 1,3-thiazolidin-4-ones, particularly the compounds 4c, 4d, 4e, 4f, 4h, 4i and 4j displays promising antitubercular activity along with no significant cytotoxicity against the cell lines MCF-7, A549 and HCT-116. (C) 2016 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Antitubercular, Cytotoxicity, Green protocol, Multicomponent reaction},
	issn = {0960-894X},
	doi = {10.1016/j.bmcl.2016.02.056},
	author = {Subhedar, Dnyaneshwar D. and Shaikh, Mubarak H. and Arkile, Manisha A. and Yeware, Amar and Sarkar, Dhiman and Shingate, Bapurao B.}
}
