%0 Journal Article %J ChemistrySelect %D 2022 %T Transition metal- and oxidant-free regioselective synthesis of 3,4,5-trisubstituted pyrazoles by means of [3+2] cycloaddition reactions %A Allaka, Bhargava Sai %A Basavoju, Srinivas %A Gamidi, Rama Krishna %K 3 %K 4 %K 5-trisubstituted pyrazoles %K Cycloaddition %K Multicomponent reaction %K Oxidant free %K Regioselectivity %K Transition metal free %X

A highly efficient regioselective synthesis of 3,4,5-trisubstituted pyrazoles via transition metal- and oxidant-free, three component [3+2] cycloaddition with thiazolidinedione chalcones, benzaldehydes and N-tosylhydrazine is described. The reaction proceeds through C-C and C-N bond formations under mild reaction conditions to produce structurally diverse polysubstituted pyrazoles in moderate to good yields.

%B ChemistrySelect %V 7 %P e202200605 %8 MAR %G eng %N 11 %9 Article %3

Foreign

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2.109

%R 10.1002/slct.202200605