%0 Journal Article %J Synthesis-Stuttgart %D 2011 %T Enantiospecific route to (+)-(1R, 3S)-cis-chrysanthemic acid from (-)-D-pantolactone(1) %A Hajare, Atul K. %A Datrange, Laxmikant S. %A Murthy, Y. L. N. %A Bhuniya, Debnath %A Reddy, D. Srinivasa %K alkenes %K Metathesis %K ring closure %K stereoselective synthesis %K Wittig reaction %X

In this paper, a novel route for the synthesis of (+)-(1R,3S)-cis-chrysanthemic acid is described. The use of readily available (-)-D-pantolactone as a starting point, application of ring-closing metathesis to form the cyclopentene intermediate, and Haller-Bauer/Grob-type fragmentation to form the target compound are the highlights of the present synthesis.

%B Synthesis-Stuttgart %I GEORG THIEME VERLAG KG %C RUDIGERSTR 14, D-70469 STUTTGART, GERMANY %P 1067-1070 %8 APR %G eng %N 7 %3 Foreign %4 2.466 %R 10.1055/s-0030-1258451