%0 Journal Article %J Advanced Synthesis & Catalysis %D 2013 %T Desymmetrization approach to the enantiopure syn/anti-1,5-diols via hydrolytic kinetic resolution (hkr) of functionalized meso-bis-epoxides: further elaboration to syn/syn-1,3,5-triols and application to the formal synthesis of cryptocarya diacetate %A Kumar, Pradeep %A Chowdhury, Partha Sarathi %A Pandey, Menaka %K bis-epoxides %K cryptocarya diacetate %K desymmetrization %K stereoselective reduction %K synthetic methods %X

A new approach has been developed for the synthesis of enantiopure syn/anti-1,5-diols by desymmetrization of functionalized meso-bis-epoxides using hydrolytic kinetic resolution (HKR). The usage of this protocol was demonstrated by converting syn-1,5-diols into syn/syn-1,3,5-triols and its subseqent application to the formal synthesis of cryptocarya diacetate.

%B Advanced Synthesis & Catalysis %I WILEY-V C H VERLAG GMBH %C BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY %V 355 %P 1719-1723 %8 JUN %G eng %N 9 %3

Foreign

%4 5.542 %R 10.1002/adsc.201300098