TY - JOUR T1 - Construction of tetrahydrobenzo[f]quinoline scaffolds via polar [4+2]-Cycloaddition reaction with arynes as dienophiles JF - Tetrahedron Letters Y1 - 2022 A1 - Pandya, Virat G. A1 - Mhaske, Santosh B. KW - Aryne KW - Diels-Alder KW - Diene KW - Tetrahydrobenzo[ f ]quinoline AB -

A transition-metal-free route has been developed for the direct synthesis of biologically significant tetrahydrobenzo[f]quinoline scaffolds. The reaction features polar [4 + 2] Diels-Alder cycloaddition reaction of arynes with a well-designed diene N-Boc protected vinyl tetrahydropyridine, followed by the isomerisation of the double bond leading to the formation of tetrahydrobenzo[f]quinoline scaffolds in good to moderate yields.

VL - 101 U3 -

Foreign

U4 -

2.032

ER -