TY - JOUR T1 - Biomimetic total synthesis of angiopterlactone B and other potential natural products JF - Organic Letters Y1 - 2017 A1 - Kotammagari, Tharun K. A1 - Gonnade, Rajesh G. A1 - Bhattacharya, Asish K. AB - A one-pot biomimetic synthesis of (-)-angiopterlactone B and its enantiomer (+)-angiopterlactone B has been accomplished via TBAF-catalyzed tandem ring contraction followed by oxa-Michael/Michael addition sequence. Comparison of specific optical rotations, absolute configurations, and CD spectra of natural, synthesized (-)-angiopterlactone B and (+)-angiopterlactone B unequivocally proves that the isolated angiopterlactone B must be levorotatory. Synthesis of hitherto undiscovered natural products 18 and 20 and analogues of angiopterlactone B demonstrate the versatility of this method. VL - 19 IS - 13 U3 - Foreign U4 - 6.732 ER -