TY - JOUR T1 - Diastereoselective synthesis of chiral 2,3-disubstituted lndolines via formal [3+2]-cycloaddition of arynes with gamma-amino-alpha,beta-unsaturated esters JF - Journal of Organic Chemistry Y1 - 2017 A1 - Aher, Ravindra D. A1 - Suryavanshi, Gurunath M. A1 - Sudalai, Arumugam AB - A one step formal [3+2]-annulation protocol for the synthesis of 2,3-disubstituted indolines is described. The in situ generated aryne acts as a two-atom component, and gamma-amino-alpha,beta-unsaturated esters acting as a three-atom component to construct indoline units in a highly regio- and diastereoselective manner with yields ranging from 63 to 80%. VL - 82 IS - 11 U3 - Foreign U4 - 4.785 ER -