TY - JOUR T1 - Efficient synthesis of gamma-keto sulfones by NHC-catalyzed intermolecular stetter reaction JF - Organic Letters Y1 - 2012 A1 - Bhunia, Anup A1 - Yetra, Santhivardhana Reddy A1 - Bhojgude, Sachin Suresh A1 - Biju, Akkattu T. AB -

The N-heterocyclic carbene-catalyzed intermolecular Stetter reaction of aldehydes with α,β-unsaturated sulfones allows the atom-economic and selective formation of γ-keto sulfones in good yields. Key to the success of this unique transition-metal-free carbon–carbon bond-forming reaction is the right choice of the NHC precursor and base. The reaction tolerates a broad range of different aldehydes.

VL - 14 IS - 11 U2 -

Council of Scientific & Industrial Research (CSIR) - India

U3 - Foreign U4 - 6.142 ER -