TY - JOUR T1 - Biocatalyst mediated functionalization of salannin, an insecticidal limonoid JF - RSC Advances Y1 - 2014 A1 - Haldar, Saikat A1 - Kolet, Swati P. A1 - Dandekar, Devdutta S. A1 - Kale, Balaji S. A1 - Gonnade, Rajesh G. A1 - Thulasiram, Hirekodathakallu V. AB -

Transformation of salannin, an insecticidal C-seco limonoid was investigated using a fungal system, Cunninghamella echinulata. Salannin was efficiently converted into two metabolites, where the C-17 furan moiety was transformed into gamma-hydroxybutenolide (salanninolide) and N-(2-hydroxyethyl)-alpha,beta-unsaturated-gamma-lactam (salanninactam) analogues. Present studies have indicated salanninolide to be a metabolite in the C-seco limonoid biosynthetic pathway.

PB - ROYAL SOC CHEMISTRY CY - THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND VL - 4 IS - 53 U3 - Foreign U4 - 3.289 ER -