TY - JOUR T1 - Croncise organocatalytic route to protected (2S, 4R)-4-hydroxyornithine and(+)-pseudohygroline JF - Synlett Y1 - 2014 A1 - Jha, Vishwajeet A1 - Kumar, Pradeep KW - aldehydes KW - Amination KW - Amino alcohols KW - cyclization KW - Enantioselectivity KW - Wittig reaction AB -

A practical, efficient, and organocatalytic approach to the synthesis of (2S,4R)-4-hydroxyornithine and (+)-pseudohygroline is reported using proline-catalyzed sequential alpha-aminoxylation/alpha-amination reaction and Horner-Wadsworth-Emmons olefination reaction of an aldehyde as the key step.

PB - GEORG THIEME VERLAG KG CY - RUDIGERSTR 14, D-70469 STUTTGART, GERMANY VL - 25 IS - 8 U3 -

Foreign

U4 -

2.323

ER -