01332nas a2200229   4500008004100000022001400041245009800055210006900153260006900222300001000291490000800301520049300309653002800802653002800830653001200858100001900870700002000889700001600909700002400925700002300949856013000972       2013                        eng d  a0022-328X00aModified zeolite immobilized palladium for ligand-free suzuki-miyaura cross-coupling reaction0 aModified zeolite immobilized palladium for ligandfree suzukimiya  aPO BOX 564, 1001 LAUSANNE, SWITZERLANDbELSEVIER SCIENCE SAcAUG  a29-340 v7383 a<p>A palladium-based catalyst supported on modified ZSM-5 was successfully prepared by a facile procedure. The prepared heterogeneous catalyst Pd@desilicated ZSM-5 showed an excellent catalytic activity at very low Pd loading (0.02 mol%) for the ligand-free Suzuki-Miyaura coupling reactions of various aryl bromides affording excellent yields of the products. The prepared catalyst presents good recyclability, over four catalytic cycles. (C) 2013 Elsevier B. V. All rights reserved.</p>10aheterogeneous catalysis10aSuzuki-Miyaura reaction10azeolite1 aKumbhar, Arjun1 aKamble, Santosh1 aMane, Anand1 aJha, Ratnesh, Kumar1 aSalunkhe, Rajashri  uhttp://library.ncl.res.in/content/modified-zeolite-immobilized-palladium-ligand-free-suzuki-miyaura-cross-coupling-reaction-002393nas a2200241   4500008004100000022001400041245012500055210006900180260000800249490000900257520156100266653002801827653002101855653001601876653001501892653002001907100001701927700002101944700001901965700002501984700001902009856012302028       2024                        eng d  a0022-328X00aCuNPs@Al2O3-cellulose composite for the ligand-free Suzuki cross-coupling reactions in batch and continuous flow process0 aCuNPsAl2O3cellulose composite for the ligandfree Suzuki crosscou  cJAN0 v10043 a<p>In the present work, we synthesized recyclable CuNPs@Al2O3-CELL composite from an inexpensive and commercially available synthetic reagent by a simple method. The catalyst was characterized by various techniques such as TGA (Thermogravimetric analysis), SEM (Scanning electron microscope), TEM (Transmission electron microscopy), XPS (X-ray photoelectron spectroscopy), EDS (Energy dispersive spectroscopy), and AAS (Atomic Absorption Spectroscopy). The composite was applied for the Suzuki coupling reactions in the batch and flow process. The aryl halides were easily coupled with arylboronic acids in 95 % ethanol at 78 C. We systematically investigated the role of reaction temperature, solvent, and catalyst loading, on the transient and steady-state behavior of the flow reactor through an automated flow chemistry platform. The CuNPs@Al2O3CELL catalytic particles demonstrate minimal deactivation and leaching over a continuous Suzuki coupling reaction at a 20 min nominal residence time at 100 C. Moreover, the catalyst can be recovered by simple filtration and reused at least five times with a moderate decrease in product yield. The excellent activity and stability of the catalyst have been attributed to the strong chelation of the Cu species with hydroxyl functional groups of the Al2O3-CELL composite. The catalytic system was highly efficient in Suzuki coupling of various aryl bromides with different aryl boronic acids, yielding good to excellent product yields (80-96 %) with a TON of 15.914-19.066 and TOF of 2.649-9.533 h(-1).</p>
10aContinuous flow process10aCuNPs@Al2O3-CELL10aligand-free10arecyclable10aSuzuki coupling1 aPatil, Seema1 aRajmane, Archana1 aJadhav, Sanjay1 aRode, Chandrashekhar1 aKumbhar, Arjun  uhttp://library.ncl.res.in/content/cunpsal2o3-cellulose-composite-ligand-free-suzuki-cross-coupling-reactions-batch-and