01545nas a2200229 4500008004100000022001400041245008800055210006900143260000800212300001100220490000800231520076100239653003201000653002001032653002401052653001701076653002601093653002801119100002701147700002701174856011401201 2022 eng d a0021-899500aReinforcement of electrospun polyurethane fibers with resorcinol-formaldehyde resin0 aReinforcement of electrospun polyurethane fibers with resorcinol cMAY ae520070 v1393 a

This work reports a simple method to improve the properties of electrospun nanofibers. The procedure involves developing nanofibers using electrospinning followed by liquid infiltration to reinforce the fibers. Coating of polyurethane nanofibers (PUN) with resorcinol-formaldehyde (RF) significantly improves the properties of PUN. Furthermore, the morphology of fiber interface and the properties of RF coated fibers indicate that RF resin reinforces the interface between the fibers. The method leads to improvement in mechanical properties of PUN. An improvement of about 94% and 281% in mechanical properties like tensile strength and modulus, respectively, compared to neat PUN fibers is achieved by coating with 20% wt/vol of RF solution.

10aDynamic mechanical analysis10aelectrospinning10aliquid infiltration10apolyurethane10areinforced nanofibers10aresorcinol-formaldehyde1 aNair, Kiran, Sukumaran1 aJames, Nirmala, Rachel uhttp://library.ncl.res.in/content/reinforcement-electrospun-polyurethane-fibers-resorcinol-formaldehyde-resin02049nas a2200229 4500008004100000022001400041245008400055210006900139260000800208300001100216490000800227520128700235653001301522653003201535653001301567653002701580653001301607100002701620700003701647700002701684856010801711 2023 eng d a0021-899500aEvaluation of the adhesive properties of vanillin-derived polyhydroxy urethanes0 aEvaluation of the adhesive properties of vanillinderived polyhyd cDec ae546470 v1403 a

Poly(hydroxy urethanes) (PHUs) have been considered attractive and safer variants of conventional polyurethanes (PUs). To improve the prerequisites of green and sustainable chemistry herein, we propose the synthesis and utilization of cyclic carbonate monomers majorly derived from vanillin, a lignin derivative, and CO2 for the development of PHUs. Kinetic evaluation on the polymerization temperature ascertained 80 degrees C as the optimum condition for PHU synthesis. The structural evaluation of PHUs was carried out by various spectroscopic techniques, such as FTIR, (HNMR)-H-1, and C-13-NMR, molar masses were determined by gel permeation chromatography (Mn varied between 2500 and 11,100 g/mol), and thermal properties evaluated by differential scanning calorimeter (Tg in the ranges of 28-42 degrees C), and thermogravimetric analysis (stable above 180 degrees C). Since the PHUs are enriched with pendant hydroxyl groups on their backbone which can promote adhesion, lap shear studies on the aluminum substrate exhibited a maximum shear strength of 1.65 +/- 0.37 MPa. This study demonstrates an attractive and environment-friendly pathway for developing novel PHUs network using renewable biobased resources and further explores its applicability as adhesives.

10aadhesive10abiobased cyclic dicarbonate10adiamines10apoly(hydroxyurethane)s10aVanillin1 aGhuge, Gorakh, Hiraman1 aKambikanam, Karthika, Vayalacher1 aNair, Kiran, Sukumaran uhttp://library.ncl.res.in/content/evaluation-adhesive-properties-vanillin-derived-polyhydroxy-urethanes02768nas a2200229 4500008004100000245012000041210006900161260000800230300001100238490000800249520195200257653002702209653001502236653003002251653002102281100002102302700001702323700002602340700002002366700002702386856012502413 2024 eng d00aBiodegradable and 3D printable lysine functionalized polycaprolactone scaffolds for tissue engineering applications0 aBiodegradable and 3D printable lysine functionalized polycaprola cMAY a2138160 v1593 a

Tissue engineering (TE) has sparked interest in creating scaffolds with customizable properties and functional bioactive sites. However, due to limitations in medical practices and manufacturing technologies, it is challenging to replicate complex porous frameworks with appropriate architectures and bioactivity in vitro. To address these challenges, herein, we present a green approach that involves the amino acid (L-lysine) initiated polymerization of epsilon-caprolactone (CL) to produce modified polycaprolactone (PCL) with favorable active sites for TE applications. Further, to better understand the effect of morphology and porosity on cell attachment and proliferation, scaffolds of different geometries with uniform and interconnected pores are designed and fabricated, and their properties are evaluated in comparison with commercial PCL. The scaffold morphology and complex internal micro-architecture are imaged by micro-computed tomography (micro-CT), revealing pore size in the range of similar to 300-900 mu m and porosity ranging from 30 to 70 %, while based on the geometry of scaffolds the compressive strength varied from 143 +/- 19 to 214 +/- 10 MPa. Additionally, the degradation profiles of fabricated scaffolds are found to be influenced by both the chemical nature and product design, where Lys-PCL-based scaffolds with better porosity and lower crystallinity degraded faster than commercial PCL scaffolds. According to in vitro studies, Lys-PCL scaffolds have produced an environment that is better for cell adhesion and proliferation. Moreover, the scaffold design affects the way cells interact; Lys-PCL with zigzag geometry has demonstrated superior in vitro vitality (>90 %) and proliferation in comparison to other designs. This study emphasizes the importance of enhancing bioactivity while meeting morphology and porosity requirements in the design of scaffolds for tissue engineering applications.

10aAdditive manufacturing10aAmino acid10aMicro-computed tomography10aPolycaprolactone1 aNaik, Sonali, S.1 aTorris, Arun1 aChoudhury, Namita, R.1 aDutta, Naba, K.1 aNair, Kiran, Sukumaran uhttp://library.ncl.res.in/content/biodegradable-and-3d-printable-lysine-functionalized-polycaprolactone-scaffolds-tissue