01561nas a2200253 4500008004100000022001400041245013400055210006900189260000800258300001400266490000800280520068000288653001800968653002100986653001801007653001701025653002901042653001701071100002401088700002501112700002401137700002101161856012501182 2019 eng d a1011-372X00aAmino acid amide based ionic liquid as an efficient organo-catalyst for solvent-free knoevenagel condensation at room temperature0 aAmino acid amide based ionic liquid as an efficient organocataly cSEP a2368-23750 v1493 a
Ionic liquids of amino acid amide were synthesized and used as an efficient catalyst for solvent-free Knoevenagel condensation. Synthesized ionic liquids are an environmentally benign, inexpensive, metal free and plays the dual role of solvent as well as an efficient catalyst for Knoevenagel condensation. A wide range of aliphatic, aromatic and heteroaromatic aldehydes easily undergo condensation with malononitrile and ethyl cyanoacetate. The reaction proceeds at room temperature without using any organic solvent and is very fast with good to excellent yield. Additionally, the catalyst is easily separable and recyclable without loss of activity. [GRAPHICS] .
10aAcrylonitrile10aAmino acid amide10aCyanoacrylate10aIonic liquid10aKnoevenagel condensation10aSolvent-free1 aBurate, Pralhad, A.1 aJavle, Balasaheb, R.1 aDesale, Pranjal, H.1 aKinage, Anil, K. uhttp://library.ncl.res.in/content/amino-acid-amide-based-ionic-liquid-efficient-organo-catalyst-solvent-free-knoevenagel