02088nas a2200289 4500008004100000022001400041245011400055210006900169260000900238300001200247490000800259520111300267653001401380653001801394653002001412653003401432653004901466653001301515653001701528100001801545700001901563700002201582700001701604700002201621700002501643856013001668 2018 eng d a0144-861700aElectrospinning of non-ionic cellulose ethers/polyvinyl alcohol nanofibers: characterization and applications0 aElectrospinning of nonionic cellulose etherspolyvinyl alcohol na cFEB a175-1820 v1813 a
The morphology of spin-coated films and electrospun fibers of ethyl hydroxy ethyl cellulose (EHEC), hydrophobically modified ethyl hydroxy ethyl cellulose (HM-EHEC) and their blends with Poly(vinyl alcohol) (PVA) was examined by AFM, SEM and contact angle measurements. These polysaccharides upon blending with PVA exhibited smooth surface which was evidenced by Atomic Force Microscopy (AFM) observation. The electrospinnability of above polysaccharides with PVA was demonstrated for the first time. The oriented fibers could be obtained using a rotating disc collector. Contact angles of spin-coated films and electrospun fibers were discussed in terms of hydrophobicity and wetting characteristics. Further, The nanofibers of EHEC/PVA were in-situ crosslinked using citric acid and were used for controlled release of an antibacterial drug, Chlorhexidine Digluconate (ChD). In-vitro studies of cytotoxicity, cell growth and cell proliferation were performed using L929 mouse fibroblast cells. These nanofiber mats show potential in drug delivery and as scaffolds in tissue engineering applications.
10acellulose10adrug delivery10aelectrospinning10aEthyl hydroxy ethyl cellulose10aHydrophobically modified ethyl hydroxy ethyl10ascaffold10aSpin coating1 aWali, Ashwini1 aZhang, Yucheng1 aSengupta, Poulomi1 aHigaki, Yuji1 aTakahara, Atsushi1 aBadiger, Manohar, V. uhttp://library.ncl.res.in/content/electrospinning-non-ionic-cellulose-etherspolyvinyl-alcohol-nanofibers-characterization-and