01330nas a2200217 4500008004100000022001400041245008300055210006900138260007300207300001200280490000600292520056600298653001800864653001500882653001400897653001400911100001800925700002900943700002900972856011101001 2007 eng d a1566-736700aRate enhancement in palladium catalyzed Heck reactions by Lewis acid promoters0 aRate enhancement in palladium catalyzed Heck reactions by Lewis aPO BOX 211, 1000 AE AMSTERDAM, NETHERLANDSbELSEVIER SCIENCE BVcFEB a183-1860 v83 a
Significant enhancement in the rate of Heck reactions has been achieved when catalytic amounts of Lewis acid (like FeCl(3)) promoters in the presence of trace amounts of water (> 2000 ppm) are used along with Pd complex catalysts. Experiments with different aryl halides, bases as well as olefins have been carried out to demonstrate the role of Lewis acid promoters. The increase in the reaction rates is due to the weakening of Ar-X bond by the Lewis acid in the manner similar to Friedel-Crafts reaction. (c) 2006 Elsevier B.V. All rights reserved.
10aHeck reaction10aLewis acid10aPalladium10aPromoters1 aSud, Abhishek1 aDeshpande, Raj, Madhukar1 aChaudhari, Raghunath, V. uhttp://library.ncl.res.in/content/rate-enhancement-palladium-catalyzed-heck-reactions-lewis-acid-promoters