01411nas a2200253 4500008004100000022001400041245011900055210006900174260010600243300001400349490000700363520042600370653002000796653002000816653003300836653003000869653002300899100002000922700002100942700002400963700002500987700001701012856012801029 2005 eng d a0040-402000aEfficient method for the synthesis of methyl 11 alpha-amino-3 alpha,7 alpha-diacetoxy-12-oxo-5 beta-cholan-24-oate0 aEfficient method for the synthesis of methyl 11 alphaamino3 alph aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcAPR a3605-36120 v613 a
The synthesis of methyl 11 alpha-azido-3 alpha,7 alpha-diacetoxy-12-oxo-5 beta-cholan-24-oate, methyl 11 beta-azido-3 alpha,7 alpha-diacetoxy-12-oxo-5 beta-cholan-24-oate and methyl 11 alpha-amino-3 alpha,7 alpha-diacetoxy-12-oxo-5 beta-cholan-24-oate have been achieved. Mechanistic aspects for the decomposition of steroidal azidoketones to its enamines are discussed. (c) 2005 Elsevier Ltd. All rights reserved.
10a11-aminosteroid10a11-azidosteroid10abase catalyzed epimerization10aHIV-1 protease inhibitors10asteroidal enamines1 aSalunke, D., B.1 aHazra, Braja, G.1 aGonnade, Rajesh, G.1 aBhadbhade, Mohan, M.1 aPore, V., S. uhttp://library.ncl.res.in/content/efficient-method-synthesis-methyl-11-alpha-amino-3-alpha7-alpha-diacetoxy-12-oxo-5-beta-0