01070nas a2200169 4500008004100000022001400041245014500055210006900200260010600269300001400375490000700389520029900396100002400695700002500719700002700744856012900771 2010 eng d a0957-416600aFacile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using the hydrolytic kinetic resolution method0 aFacile enantioselective synthesis of enantiomerically pure Rphen aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcDEC a2825-28290 v213 a
A practical and highly efficient enantioselective synthesis of (R)-phenoxybenzamine hydrochloride has been described for the first time using Jacobsen's hydrolytic kinetic resolution of a terminal epoxide as a key step and source of chirality. (C) 2010 Elsevier Ltd. All rights reserved.
1 aNikalje, Milind, D.1 aSasikumar, Murugesan1 aMuthukrishnan, Murugan uhttp://library.ncl.res.in/content/facile-enantioselective-synthesis-enantiomerically-pure-r-phenoxybenzamine-hydrochloride-0