01058nas a2200157 4500008004100000022001400041245012700055210006900182260010600251300001400357490000700371520035800378100002300736700002400759856011700783 2010 eng d a0040-403900aIn situ, on-resin synthesis of 8-Br/NH2 adeninyl peptide nucleic acid (PNA) oligomers and complementation studies with DNA0 aIn situ onresin synthesis of 8BrNH2 adeninyl peptide nucleic aci aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcDEC a6560-65640 v513 a
A new, novel and efficient in situ synthesis of 8-aminoadeninyl PNA oligomers from corresponding 8-bromoadeninyl PNA oligomers is reported. The study of hybridisation properties of (8-Br/8-NH2) PNA oligomers with cDNA reveals substitution-site dependent stabilization of derived triplexes and duplexes. (C) 2010 Elsevier Ltd. All rights reserved.
1 aVysabhattar, Raman1 aGanesh, Krishna, N. uhttp://library.ncl.res.in/content/situ-resin-synthesis-8-brnh2-adeninyl-peptide-nucleic-acid-pna-oligomers-and-0