01395nas a2200229 4500008004100000022001400041245025400055210006900309260007700378300001400455490000800469520037400477653001700851653002600868653002100894653003000915653002200945100001900967700003100986700001901017856012901036 2013 eng d a1615-415000aDesymmetrization approach to the enantiopure syn/anti-1,5-diols via hydrolytic kinetic resolution (hkr) of functionalized meso-bis-epoxides: further elaboration to syn/syn-1,3,5-triols and application to the formal synthesis of cryptocarya diacetate0 aDesymmetrization approach to the enantiopure synanti15diols via aBOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANYbWILEY-V C H VERLAG GMBHcJUN a1719-17230 v3553 a
A new approach has been developed for the synthesis of enantiopure syn/anti-1,5-diols by desymmetrization of functionalized meso-bis-epoxides using hydrolytic kinetic resolution (HKR). The usage of this protocol was demonstrated by converting syn-1,5-diols into syn/syn-1,3,5-triols and its subseqent application to the formal synthesis of cryptocarya diacetate.
10abis-epoxides10acryptocarya diacetate10adesymmetrization10astereoselective reduction10asynthetic methods1 aKumar, Pradeep1 aChowdhury, Partha, Sarathi1 aPandey, Menaka uhttp://library.ncl.res.in/content/desymmetrization-approach-enantiopure-synanti-15-diols-hydrolytic-kinetic-resolution-hkr-0