@article {46108, title = {Transition-metal-free glucose-derived carbonaceous catalyst catalyzes direct C-H arylation of unactivated arenes with aryl halides}, journal = {ChemistrySelect}, volume = {4}, year = {2019}, month = {MAY }, pages = {4848-4853}, type = {Article}, abstract = {

Transition metal free coupling reactions have gained lot of importance recently. The traditional method for the synthesis of biaryl{\textquoteright}s uses organometallic reagents for the arylation reactions. There are certain drawbacks associated with such traditional methods. Use of expensive metals, metal impurities in the products formed and disposal of metal waste generated are major problems that need to be taken care of. Thus, research has been focussed on using transition metal free catalyst for cross coupling reactions to encourage green environment and it still remains a challenge for researchers. Carbonaceous catalyst have attracted great attention recently as a heterogeneous catalyst as it has a carbon skeleton that is stable, easily separable, reusable, eco-friendly and highly economical compared to other heterogeneous catalyst. Carbonaceous catalysts have been studied in variety of organic reactions such as hydrolysis, dehydration, esterification, alkylation, condensation, oxathioketalization, dimerization, benzylation and trimethylsilylation, etc. It was estimated that - stacking interactions between carbonaceous catalyst and arenes will accelerate the coupling reaction. However to the best of our knowledge, there are no reports available in literature on use of carbonaceous catalyst for direct arylation of arenes. And thus, we developed a new method for C-H arylation of unactivated arenes with aryl halides using a transition metal free D-glucose derived carbonaceous catalyst.

}, keywords = {Arylation, carbonaceous, glucose, metal-free}, issn = {2365-6549}, doi = {10.1002/slct.201900013}, author = {Jori, Popat K. and Jadhav, Vrushali H.} } @article {48042, title = {Metal- and light-free direct C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols in aqueous medium}, journal = {ChemistrySelect}, volume = {7}, year = {2022}, month = {OCT}, pages = {e202203597}, type = {Article}, abstract = {

Direct oxidative C-3 ketoalkylation of quinoxalin-2(1H)-ones with cyclopropanols using ammonium persulfate in an aqueous medium has been achieved in a moderate to good yield. The reaction does not require metals, light-source, or catalysts to facilitate the reaction and could be efficiently utilized to construct a wide range of biologically relevant 3-ketoalkylated quinoxalin-2(1H)-ones.

}, keywords = {aqueous medium, cyclopropanols, ketoalkylation, metal-free, quinoxalin-2(1H)-ones}, issn = {2365-6549}, doi = {10.1002/slct.202203597}, author = {More, Devidas A. and Mujahid, M. and Muthukrishnan, M.} } @article {48024, title = {Metal-free access to hindered N-alkyl sulfoximines via in-situ generated Aza-oxyallyl cations from functionalized alkyl bromide}, journal = {Asian Journal of Organic Chemistry}, volume = {11}, year = {2022}, month = {JUL}, pages = {e202200210}, type = {Article}, abstract = {

Herein, we report a catalyst-free and mild synthetic method for the construction of hindered N-alkyl sulfoximines derivative. A wide range of hindered di-alkyl sulfoximines can be readily obtained from the reaction of alpha-bromo-hydroxamates with a variety of sulfoximines, including diaryl, aryl-alkyl, di-alkyl and heteroaryl sulfoximines.

}, keywords = {alpha-Bromo hydroxamates, Aza-oxyallyl cations, Di-alkyl sulfoximines, metal-free, Sulfoximines}, issn = {2193-5807}, doi = {10.1002/ajoc.202200210}, author = {More, Satish G. and Mane, Kishor D. and Suryavanshi, Gurunath} }