@article { ISI:000278307300033,
	title = {Ring opening polymerization of dilactide using salen complex as catalyst},
	journal = {Materials Science and Engineering B-Advanced Functional Solid-State Materials},
	volume = {168},
	number = {1-3, SI},
	year = {2010},
	note = {Conference on Specialty Advanced Materials and Polymers for Aerospace and Defense and Applications (SAMPADA-2008), Mat Res Soc Singapore, Singapore, SINGAPORE, JUL 03-08, 2005},
	month = {APR},
	pages = {193-198},
	publisher = {ELSEVIER SCIENCE BV},
	address = {PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS},
	abstract = {<p>The recent concerns about our environment have led to search for environmentally benign and sustainable materials that could substitute the more commonly used petroleum based materials. Biodegradable and sustainable polylactide (PLA) is becoming one of the most promising and practical materials as a partial replacement for the petroleum-based materials. The commercially available PLA is generally homochiral poly(L-lactide) (PLLA) at present because L-lactic acid with high optical purity can only be obtained in bulk by fermentation of carbohydrate. PLLA is mostly synthesized by ring opening polymerization (ROP) of homochiral L-lactide (LLA), which is a cyclic dimer of L-lactic acid. In the present work, poly(L-lactide)s were synthesized by the ring opening polymerization (ROP) of L-lactide using iron and manganese salen complexes as catalyst. The new iron and manganese salen complexes were synthesized, purified, characterized and used as catalyst for polymerization of L-lactide. The poly(L-lactide)s prepared were characterized by infrared, proton NMR spectroscopy, solution viscosity, gel permeation chromatography, thermal analysis and X-ray diffraction. (C) 2009 Elsevier B.V. All rights reserved.</p>},
	keywords = {Gel permeation chromatography, Iron salen catalyst, L-Lactic acid, L-Lactide, Manganese salen catalyst, Poly(L-lactide), ring opening polymerization, Solution viscosity},
	issn = {0921-5107},
	doi = {10.1016/j.mseb.2009.10.037},
	author = {Idage, Bhaskar B. and Idage, Susheela B. and Kasegaonkar, A. S. and Jadhav, R. V.}
}
@article { ISI:000316812800023,
	title = {Facile strategy for synthesis of ,-heterobifunctionalized poly (epsilon-caprolactones) and poly (methyl methacrylate)s containing {\textquoteleft}{\textquoteleft}clickable{\textquoteright}{\textquoteright} aldehyde and allyloxy functional groups using initiator approach},
	journal = {Journal of Polymer Science Part A-Polymer Chemistry},
	volume = {51},
	number = {9},
	year = {2013},
	month = {MAY},
	pages = {2091-2103},
	publisher = {WILEY-BLACKWELL},
	address = {111 RIVER ST, HOBOKEN 07030-5774, NJ USA},
	abstract = {<p>Two new initiators, namely, 4-(4-(2-(4-(allyloxy) phenyl)-5-hydroxypentane 2-yl) phenoxy)benzaldehyde and 4-(4-(allyloxy) phenyl)-4-(4-(4-formylphenoxy) phenyl) pentyl 2-bromo-2-methyl propanoate containing clickable hetero-functionalities namely aldehyde and allyloxy were synthesized starting from commercially available 4,4-bis(4-hydroxyphenyl) pentanoic acid. These initiators were utilized, respectively, for ring opening polymerization of epsilon-caprolactone and atom transfer radical polymerization of methyl methacrylate. Well-defined -aldehyde, -allyloxy heterobifunctionalized poly(epsilon-caprolactones) (Mn,GPC: 590029,000, PDI: 1.261.43) and poly(methyl methacrylate)s (Mn,GPC: 530028800, PDI: 1.191.25) were synthesized. The kinetic study of methyl methacrylate polymerization demonstrated controlled polymerization behavior. The presence of aldehyde and allyloxy functionality on polymers was confirmed by 1H NMR spectroscopy. Aldehyde-aminooxy and thiol-ene metal-free double click strategy was used to demonstrate reactivity of functional groups on polymers. (c) 2013 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2013, 51, 2091-2103</p>},
	keywords = {atom transfer radical polymerization, Click chemistry, functional polymers, ring opening polymerization},
	issn = {0887-624X},
	doi = {10.1002/pola.26598},
	author = {Sane, Prakash S. and Tawade, Bhausaheb V. and Parmar, Indravadan and Kumari, Savita and Nagane, Samadhan and Wadgaonkar, Prakash P.}
}
@article {47617,
	title = {Evaluation of biocompatibility of synthesized low molecular weight PLGA copolymers using zinc L-proline through green route for biomedical application},
	journal = {Polymers for Advanced Technologies},
	volume = {32},
	year = {2021},
	month = {NOV},
	pages = {4502-4515},
	type = {Article},
	abstract = {Poly(lactide-co-glycolide) (PLGA) copolymers were synthesized by ring opening polymerization in presence of zinc proline and stannous octoate in bulk through green route and were designated as PLGA-1 and PLGA-2 respectively. These copolymers were characterized using NMR, SEC, DSC, X-ray and MALDI-TOF analysis. For the first time, the low molecular weight of PLGA (similar to 11,000 Da) was mainly targeted to explore acute oral toxicity in the presence of zinc L-proline and stannous octoate. The haemolysis and cell viability assay were carried out for in-vitro cytotoxicity assessment. Haemolysis assay of PLGA-2 was confirmed and haemolytic potential exceeded limit of American society of testing of material standard. The cell viability study using fibroblast cell lines (NIH3T3), exhibited statistically significant difference in results between PLGA-1 and PLGA-2. The acute toxicity study was performed in Balb/c mice for biomarker, hematological and histopathological analysis. No mortality was observed during the entire observation period, and no macroscopic change of the organs was observed in PLGA-1 treated group where PLGA-2 treated group showed sign of toxicity. The results obtained from in-vitro and in-vivo studies suggested that PLGA-2 was toxic whereas PLGA-1 was nontoxic in nature. Therefore, PLGA-1 can be regarded as biocompatible biomaterials for potential for drug delivery and biomedical application.},
	keywords = {OECD-420, poly (lactide-co-glycolide), ring opening polymerization, Stannous octoate, zinc L-Proline},
	issn = {1042-7147},
	doi = {10.1002/pat.5452},
	author = {Giram, Prabhanjan S. and Garnaik, Baijayantimala}
}
