@article { ISI:000286789100007,
	title = {Target cum flexibility: an alkyne [2+2+2]-cyclotrimerization strategy for synthesis of trinem library},
	journal = {Tetrahedron Letters},
	volume = {52},
	number = {1},
	year = {2011},
	month = {JAN},
	pages = {38-41},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A rapid access to the central 4,5,6-tricyclic core of 4,5,6-trinems has been achieved by employing the alkyne [2+2+2]-cyclotrimerization as the key and final reaction in the synthesis. (C) 2010 Elsevier Ltd. All rights reserved.</p>},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2010.10.123},
	author = {Ramana, C. V. and Dushing, Mangesh P. and Mohapatra, Sradhanjali and Mallik, Rosy and Gonnade, Rajesh G.}
}
@article { ISI:000294145600011,
	title = {Target cum flexibility: synthesis of C(3 {\textquoteleft})-spiroannulated nucleosides},
	journal = {Tetrahedron Letters},
	volume = {52},
	number = {36},
	year = {2011},
	month = {SEP},
	pages = {4627-4630},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>We report a simple strategy for the synthesis of a collection of C(3{\textquoteright})-spirodihydroisobenzo-furannulated nucleosides featuring a [2+2+2]-cyclotrimerization as the key reaction. The cyclotrimerization reactions are facile with the unprotected nucleosides having a diyne unit. When both alkynes of the diyne are terminal, the regioselectivity is poor. However, when one of the terminal alkynes is additionally substituted, the cyclotrimerizations are highly diastereoselective. Since the key bicycloannulation is the final step, this strategy provides flexibility in terms of the alkynes and is thus amenable for the synthesis of a focussed small molecule library. (C) 2011 Published by Elsevier Ltd.</p>},
	keywords = {Dihydroisobenzofuran, Modified nucleosides, Tanaka catalyst, Willkinson catalyst, [2+2+2]-Cyclotrimerization},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2011.06.100},
	author = {Dushing, Mangesh P. and Ramana, C. V.}
}
