@article { ISI:000287277700038,
	title = {Quantum dot based immunosensor using 3D circular microchannels fabricated in PDMS},
	journal = {Biosensors \& Bioelectronics},
	volume = {26},
	number = {6},
	year = {2011},
	month = {FEB},
	pages = {3050-3053},
	publisher = {ELSEVIER ADVANCED TECHNOLOGY},
	type = {Article},
	address = {OXFORD FULFILLMENT CENTRE THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND},
	abstract = {<p>Microchannel is basic functional component of microfluidic chip and every step-forward of its construction technique has been receiving concern all over the world. The present work describes a novel, rapid and simple fabrication technique for building 3D microchannels in poly(dimethyl siloxane) (PDMS) elastomer. These microchannels were used for rapid detection of antigens (E. coli) by quantum dot (QD) based approach. Luminescent QD (CdTe) were synthesized by aqueous method and characterized using high resolution transmission electron microscopy (HRTEM), fluorescence spectroscopy and X-ray diffraction (XRD). The QDs were functionalized with anti-E. coli antibodies for immuno-detection. The reported process allowed easier and faster method of fabrication of circular 3D micochannels and demonstrated their potential use in an immuno-biosensor device. (C) 2010 Elsevier B.V. All rights reserved.</p>},
	keywords = {Capillary driven flows, Circular microfluidics, Immunosensor, QDs},
	issn = {0956-5663},
	doi = {10.1016/j.bios.2010.12.017},
	author = {Morarka, Amit and Agrawal, Shailaja and Kale, Sonia and Kale, Anup and Ogale, Satishchandra B. and Paknikar, Kishore and Bodas, Dhananjay S.}
}
@article { ISI:000302639600011,
	title = {Quantum dot bio-conjugate: as a western blot probe for highly sensitive detection of cellular proteins},
	journal = {Journal of Nanoparticle Research},
	volume = {14},
	number = {3},
	year = {2012},
	month = {MAR},
	pages = {732},
	publisher = {SPRINGER},
	address = {VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS},
	abstract = {<p>In the present study, we report a quantum dot (QD)-tailored western blot analysis for a sensitive, rapid and flexible detection of the nuclear and cytoplasmic proteins. Highly luminescent CdTe and (CdTe) ZnS QDs are synthesized by aqueous method. High resolution transmission electron microscopy, Raman spectroscopy, fourier transform infrared spectroscopy, fluorescence spectroscopy and X-ray diffraction are used to characterize the properties of the quantum dots. The QDs are functionalized with antibodies of prostate apoptosis response-4 (Par-4), poly(ADP-ribose) polymerases and beta actin to specifically bind with the proteins localized in the nucleus and cytoplasm of the cells, respectively. The QD-conjugated antibodies are used to overcome the limitations of conventional western blot technique. The sensitivity and rapidity of protein detection in QD-based approach is very high, with detection limits up to 10 pg of protein. In addition, these labels provide the capability of enhanced identification and localization of marker proteins in intact cells by confocal laser scanning microscopy.</p>},
	keywords = {Detection, Imaging, nanomedicine, quantum dot, Rapid, sensors, Western blot},
	issn = {1388-0764},
	doi = {10.1007/s11051-012-0732-9},
	author = {Kale, Sonia and Kale, Anup and Gholap, Haribhau and Rana, Abhimanyu and Desai, Rama and Banpurkar, Arun G. and Ogale, Satishchandra and Shastry, Padma}
}
