@article {42651,
	title = {Synthesis and characterization of novel value added biodegradable poly(aleuritic acid) from renewable resources(shellac) and invertible amphiphilic behaviors in various solvents},
	journal = {E-Polymer},
	year = {2010},
	month = {NOV},
	pages = {Article Number: 131},
	abstract = {<p>A novel biodegradable polymer poly(aleuritic acid) (PAA) ( M̄w 120,000) was prepared from aleuritic acid, which was obtained from renewable resources (Lac) by using tin catalyst. Aleuritic acid (AL) was protected at 9, 10 position by dimethoxy propane. The protected AL (Pro.AL) was further polymerized to obtain linear protected polyaleuritic acid (PAL) by dehydropolycondensation. Effects of various kinetic and thermodynamic parameters were studied. After polymerization, the deprotection of PAL was carried out. The synthesized PAL and PAA were characterized by using various techniques such as FT-IR, LC-MS, SEC, NMR (1H and 13C), 13C CP/MAS (Cross Polarization / Magic Angle Spinning) of solid PAA, DSC, SEM and TEM etc. The micelle and inverted micelle -structure in polar and nonpolar solvents are highlighted</p>},
	doi = {10.1515/epoly.2010.10.1.1476},
	author = {Pandey, Asutosh K. and Nande, Smita S. and Selukar, Balaji S. and Garnaik, Baijayantimala}
}
@article { ISI:000333686000001,
	title = {Synthesis of ciprofloxacin-conjugated poly(L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation},
	journal = {International Journal of Nanomedicine},
	volume = {9},
	year = {2014},
	month = {MAR},
	pages = {1463-1477},
	publisher = {DOVE MEDICAL PRESS LTD},
	address = {PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND},
	abstract = {<p>Ciprofloxacin was conjugated with polylactide (PLA) via the secondary amine group of the piperazine ring using PLA and 7-(4-(2-Chloroacetyl) piperazin-1-yl)-1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxoquinoline-3-carboxylic acid. Zinc prolinate, a biocompatible catalyst was synthesized, characterized, and used in ring opening polymerization of L-lactide. Five different kinds of OH-terminated poly(L-lactide) (two-, three-, four-, six-arm, star-shaped) homopolymers were synthesized by ring opening polymerization of L-lactide in the presence of dodecanol, glycerol, pentaerythritol, dipentaerythritol as initiator and zinc prolinate as a catalyst. The structures of the polymers and conjugates were thoroughly characterized by means of gel permeation chromatography, matrix-assisted laser desorption/ionization-time of flight mass spectrometry, and nuclear magnetic resonance spectroscopy. PLA (molecular weight = 100,000) and ciprofloxacin conjugated PLA were used for fabrication of nonwoven nanofiber mat (diameter ranges; 150-400 nm) having pore size (62-102 nm) using electrospinning. The microbiological assessment shows that the release of ciprofloxacin possesses antimicrobial activity. The drug-release behavior of the mat was studied to reveal potential application as a drug delivery system. The result shows that the ciprofloxacin release rates of the PLA conjugate nonwoven nanofiber mat could be controlled by the drug loading content and the release medium. The development of a biodegradable ciprofloxacin system, based on nonwoven nanofiber mat, should be of great interest in drug delivery systems.</p>},
	keywords = {antibacterial activity, ciprofloxacin conjugated polylactides, CP-PLA, drug release, electrospinning, MDR, nonwoven nanofibers, zinc prolinate},
	issn = {1178-2013},
	doi = {10.2147/IJN.S54971},
	author = {Parwe, Sharad P. and Chaudhari, Priti N. and Mohite, Kavita K. and Selukar, Balaji S. and Nande, Smita S. and Garnaik, Baijayantimala}
}
@article {44150,
	title = {Organo-clay hybrid hydrophobic spherical styrene divinylbenzene crosslink beads for high-performance carbon dioxide capture},
	journal = {New Journal of Chemistry},
	volume = {41},
	year = {2017},
	month = {OCT},
	pages = {12326-12335},
	type = {Article},
	abstract = {Herein, we report carbon dioxide sorption properties for a series of cloisite-containing crosslink hybrid materials. These materials were prepared by copolymerizing styrene divinylbenzene in the presence of various cloisites through suspension polymerization in one pot to obtain uniform spherical beads. The homopolymer formed during the polymerization was separated from the hybrid. The synthetic strategy is user-friendly and cost-effective, can be easily scaled up for production, and provides materials with good mechanical strength. The microporous polymeric spheres containing organo-clay (cloisite) showed a high surface area of similar to 80-370 m(2) g(-1) with a microsphere size of similar to 4.4 nm. These polymeric spherical beads were hydrophobic and thermally stable up to 300 degrees C. They showed high carbon dioxide uptake (up to similar to 20.7 wt\% at 273 K/1.0 bar) due to lone pair electrons of heteroatom, which might sharpen the interaction between the CO2 molecules and polymeric matrices through local dipole/quadruple interaction. Moreover, they showed good capacity to store CO2 due to the presence of quaternary ammonium groups in the clay and a large amount of narrow microspheres (B4.4 nm). The equilibrium CO2 capacities of the prepared spherical beads were due to the interaction between quaternary ammonium and the negatively charged oxygen atoms of CO2, and these spherical beads showed potential applications in gas adsorption and separation.},
	doi = {10.1039/c7nj02141k},
	author = {Nande, Smita S. and Garnaik, Baijayantimala}
}
@article {45393,
	title = { Fast dissolving moxifloxacin hydrochloride antibiotic drug from electrospun Eudragit L-100 nonwoven nanofibrous mats},
	journal = {Materials Science \& Engineering C-Materials For Biological Applications },
	volume = {92},
	year = {2018},
	month = {NOV},
	pages = { 526-539},
	type = {Article},
	abstract = {Antimicrobial electrospun nonwoven Eudragit L-100 nanofibrous mats containing Moxifloxacin hydrochloride (MOX-HCL) were fabricated for fast dissolving drug delivery systems (DDSs) associated with wound infection. The morphological characterization of nanofibers using ESEM revealed that the average diameter of non-woven nanofibrous mats ranges 200-600 nm. The nanofiber showed cylindrical shape with crack on the surface. Differential scanning calorimetric (DSC) and Wide Angle X-ray diffraction (WAXRD) demonstrate that the drug exists in an amorphous state in the nanofibers. Nanofibrous mats were also tested for mechanical strength, contact angle, swelling assay, haemolysis and disintegration test. In vitro disintegration tests demonstrated that the dissolution of Eudragit L-100 fiber mats was within 25 s which was higher compared to the pure drug. The Eudragit nanofibers showed pH-dependent drug release profiles, with slow release at pH 1.2 and burst release (around 30 s) at pH 6.8. The in-vitro quantitative and qualitative antimicrobial assay showed that the developed Eudragit L-100 nanofibrous mats with MOX-HCL concentration of 1\%, 5\% and 15 wt\% exhibited antibacterial activities against both gram positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria. The invitro cytotoxicity assay using mouse fibroblast NIH/3T3 cells demonstrated significant biocompatibility of nanofiber mats. As per the results of biological evaluation, Eudragit L-100 nanofibrous mats with 1wt\% MOX-HCL could be a suitable substrate for biomedical applications. Eudragit L-100 nanofibrous mats containing Moxifloxacin hydrochloride (MOX-HCL) showed immediate DDSs for localized drug release in the wound infection at slightly acidic or alkaline conditions where faster drug release rate is required for wound healing.},
	issn = {0928-4931},
	doi = {10.1016/j.msec.2018.06.031},
	author = {Giram, Prabhanjan S. and Shitole, Ajinkya and Nande, Smita S. and Sharma, Neeti and Garnaik, Baijayantimala}
}
