@article { ISI:000230023600015,
	title = {Expedient synthesis of 1,2,3-triazole-fused tetracyclic compounds by intramolecular Huisgen ({\textquoteright}click{\textquoteright}) reactions on carbohydrate-derived azido-alkynes},
	journal = {Tetrahedron Letters},
	volume = {46},
	number = {27},
	year = {2005},
	month = {JUL},
	pages = {4585-4588},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>An efficient, practical and convenient synthesis of 1,2,3-triazole-fused tetracyclic compounds was achieved by intramolecular 1,3-dipolar cycloaddition of carbohydrate-derived azido-alkynes. (c) 2005 Elsevier Ltd. All rights reserved.</p>},
	keywords = {carbohydrates, Click chemistry, Cycloaddition, diversity oriented synthesis, Huisgen reaction},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2005.05.012},
	author = {Hotha, Srinivas and Anegundi, Ramakrishna I. and Natu, A. A.}
}
@article { ISI:000286732600010,
	title = {Enhanced DNA binding of 9-omega-amino alkyl ether analogs from the plant alkaloid berberine},
	journal = {DNA and Cell Biology},
	volume = {30},
	number = {2},
	year = {2011},
	month = {FEB},
	pages = {123-133},
	publisher = {MARY ANN LIEBERT, INC},
	address = {140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA},
	abstract = {<p>To understand the structure-activity relationship of isoquinoline alkaloids, absorption, fluorescence, circular dichroism, and thermodynamics were employed to study the interaction of five C-9-omega-amino alkyl ether analogs from the plant alkaloid berberine with double-stranded calf thymus DNA. The C-9 derivatization resulted in dramatic enhancements in the fluorescence emission of these compounds. The most remarkable changes in the spectral and binding properties were in the BC4 and BC5 derivatives. Interactions of these analogs, which have an additional recognition motif with DNA, were evaluated through different spectroscopic and calorimetric titration experiments. The analogs remarkably enhanced the DNA binding affinity and the same was directly dependent on the alkyl chain length. The analog with six alkyl chains enhanced the DNA binding affinity by about 33 times compared with berberine. The binding became more entropically driven with increasing chain length. These results may be of potential use in the design of berberine derivatives and understanding of the structure-activity relationship for improved therapeutic applications.</p>},
	issn = {1044-5498},
	doi = {10.1089/dna.2010.1109},
	author = {Islam, Md Maidul and Basu, Anirban and Hossain, Maidul and Sureshkumar, Gopalsamy and Hotha, Srinivas and Kumar, Gopinatha Suresh}
}
@article { ISI:000335134300022,
	title = {Engineered glucose to generate a spectroscopic probe for studying carbohydrate biology},
	journal = {Advances in Experimental Medicine and Biology},
	volume = {749},
	year = {2012},
	note = {International Symposium on the Biochemical Role of Eukaryotic Cell Surface Macromolecules, Trivandrum, INDIA, JAN, 2011},
	month = {APR},
	pages = {313-327},
	publisher = {SPRINGER-VERLAG BERLIN},
	address = {HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY},
	isbn = {978-1-4614-3380-4; 978-1-4614-3381-1},
	issn = {0065-2598},
	doi = {10.1007/978-1-4614-3381-1_21},
	author = {Tripathi, Ashish and Singh, Vibha and Aishwarya, K. G. and Aradhyam, Gopala Krishna and Hotha, Srinivas},
	editor = {Sudhakaran, PR and Surolia, A}
}
