@article { ISI:000312145400009, title = {First total synthesis of seimatopolide B}, journal = {RSC Advances}, volume = {2}, number = {30}, year = {2012}, month = {OCT}, pages = {11231-11234}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

The first enantioselective total synthesis of seimatopolide B has been achieved, using ring-closing metathesis and DCC (N,N{\textquoteright}-dicyclohexylcarbodiimide) coupling as key steps. The stereogenic centres were generated by means of iterative hydrolytic kinetic resolution (HKR) of racemic epoxides.

}, issn = {2046-2069}, doi = {10.1039/c2ra21838k}, author = {Nookaraju, U. and Harbindu, Anand and Bhise, Ankushkumar D. and Sharma, Brijesh M. and Kumar, Pradeep} } @article { ISI:000340872300007, title = {Clay-supported copper nitrate (Claycop): a mild reagent for the selective nitration of aromatic olefins}, journal = {Synlett}, volume = {25}, number = {14}, year = {2014}, month = {SEP}, pages = {1997-2000}, publisher = {GEORG THIEME VERLAG KG}, type = {Article}, address = {RUDIGERSTR 14, D-70469 STUTTGART, GERMANY}, abstract = {

A straightforward and highly selective method has been developed for the nitration of a wide variety of aromatic and aliphatic olefins by using a clay-supported copper nitrate (Claycop) and a catalytic amount of (2,2,6,6-tetramethylpiperidin-1-yl)oxyl, an inexpensive and mild reagent system. High conversions and exclusive E-selectivity, together with the environmentally benign nature of the Claycop reagent, make this a green method and an attractive alternative to established methods.

}, keywords = {alkenes, nitrations}, issn = {0936-5214}, doi = {10.1055/s-0034-1378513}, author = {Begari, Eeshwaraiah and Singh, Chandani and Nookaraju, U. and Kumar, Pradeep} } @article { ISI:000358734800021, title = {Total synthesis of (+)-petromyroxol via tandem alpha-aminoxylation-allylation and asymmetric dihydroxylation-S(N)2 cyclization approach}, journal = {RSC Advances}, volume = {5}, number = {78}, year = {2015}, month = {JUL}, pages = {63311-63317}, publisher = {ROYAL SOC CHEMISTRY}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

The total synthesis of (+)-petromyroxol, a tetrahydrofuran (THF)-diol fatty acid, isolated from sea lamprey larvae (Petromyzon marinus) is reported. The present synthesis employs a tandem alpha-aminoxylationallylation, cross metathesis and tandem asymmetric dihydroxylation-S(N)2 cyclization as key steps.

}, issn = {2046-2069}, doi = {10.1039/c5ra10405j}, author = {Nookaraju, U. and Kumar, Pradeep} } @article {43373, title = {CeCl3 center dot 7H(2)O-NaI promoted regioselective sulfenylation of indoles with sulfonylhydrazides}, journal = {Chemistryselect}, volume = {1}, year = {2016}, month = {JAN}, pages = {81-85}, abstract = {A simple and highly efficient method has been developed for the regioselective sulfenylation of a wide variety of indoles with alkyl and aryl sulfonylhydrazides as a sulphur source and CeCl3 center dot 7H(2)O-Nal as an inexpensive and readily available reagent system. This method involves the breaking of sulfur-oxygen and sulfur-nitrogen bonds and making of carbon-sulfur bond. The method provides high yields of the products with enhanced regioselectivity. We studied the reactivity of various electron rich and electron deficient indoles towards the sulfe-nylation reaction. The indoles containing electron donating group reacts fast towards the sulfenylation reaction as compared to the indoles containing electron withdrawing groups. More over functional groups like alkoxy, aryloxy, bromo, nitro, cyano, ester, were well tolerated under the established reaction conditions. We also proposed a plausible mechanism for this transformation. The experimental simplicity and environmentally benign nature of the reagent system makes this method an attractive alternative to established methods.}, doi = {10.1002/slct.201500014}, author = {Nookaraju, U. and Begari, Eeshwaraiah and Yetra, Ravikiran Reddy and Kumar, Pradeep} }