@article {48083,
	title = {Efficient route to 3,3 {\textquoteleft}-biindolinylidene-diones by iron-catalyzed dimerization of isatins},
	journal = {Chemistry-an Asian Journal},
	volume = {17},
	year = {2022},
	month = {AUG},
	pages = {e202200414},
	type = {Article},
	abstract = {<p>
	Iron-catalyzed dimerization of various isatin derivatives is described for the efficient synthesis of 3,3 {\textquoteleft}-biindolinylidene-diones (isoindigos). The reaction provides easy access to self-coupled and cross-coupled 3,3 {\textquoteleft}-indolinylidene-diones that have high relevance to biology and materials. This Fe(0)- or Fe(II)-catalyzed dimerization reaction tolerates a wide range of functionalities, such as fluoro, chloro, bromo, alkenyl, nitrile, ether, ester, pyrrolyl, indolyl and carbazolyl groups, including cyclic and acyclic alkyls as well as an alkyl-bearing fatty-alcohol moiety. Especially, the coupling between two distinct isatins provided excellent selectivity for the cross-dimerization with trace of self-couplings. The single-crystal X-ray diffraction study established the molecular structure of eight dimerized products. A preliminary mechanistic study of the Fe-catalyzed dimerization supported the radical pathway for the reaction.</p>
},
	keywords = {Cross-coupling, dimerization, iron, Isatin, Isoindigo, Mechanism},
	issn = {1861-4728},
	doi = {10.1002/asia.202200414},
	author = {Jagtap, Rahul A. and Pradhan, Chandini and Gonnade, Rajesh G. and Punji, Benudhar}
}
@article {49125,
	title = {Advances in the iron-catalyzed direct functionalizations of heterocycles},
	journal = {Synlett},
	volume = {34},
	year = {2023},
	month = {APR},
	pages = {683-697},
	type = {Article},
	abstract = {<p>
	Direct functionalization of heterocycles is an advanced strategy for diversifying privileged and biorelevant heterocycle-containing molecules. Particularly, use of the most abundant transition metal, iron, as a catalyst makes this process highly cost-effective and sustainable. Recently, some progress has been realized towards the direct functionalization of heterocycles under iron catalysis. Herein, we present the developments in the C-H bond functionalizations and related reactions of various heterocycles by abundant iron salts. This Synpacts is categorized into different sections based on heterocycles being functionalized, and each section is discussed based on the type of reaction catalyzed by iron. 1 Introduction 2 Functionalization of Indoles 2.1 Alkylation 2.2 Alkenylation 2.3 Other Reactions 3 Oxindoles and isatins 3.1 C-C Bond Formation 3.2 C-Heteroatom Bond Formation 4 Pyridines and Furans 5 Functionalization of Azoles 6 Summary and Outlook</p>
},
	keywords = {Alkylation, azoles, C-H functionalization, heterocycles, indoles, iron, Mechanism},
	issn = {0936-5214},
	doi = {10.1055/a-1890-8503},
	author = {Pradhan, Chandini and Punji, Benudhar}
}
