@article {47351,
	title = {Gold-catalysed nitroalkyne cycloisomerization - synthetic utility},
	journal = {Chemical Record},
	volume = {21},
	year = {2021},
	month = {DEC},
	type = {Article},
	abstract = {<p>The gold-catalysed intramolecular redox cyclization of o-alkynylnitrobenzens documented by Professors Naoki Asao and Yoshinori Yamamoto is an important discovery that has opened two complementary research domains. Advancing this cyclization with other metals as well as developing new methods around the products that result from this reaction is one aspect that has seen growing interest. On the other hand, the idea of generating alpha-oxo gold carbenes via oxygen transfer to alkynes has established another important aspect in gold-catalysis. In this account, we will be dealing with the first aspect, which revolves around the internal redox cyclization of nitroalkynes (trivially called as nitroalkyne cycloisomerization), focusing mainly on the gold-complexes and the synthetic methods developed around it from our group and from other groups, and also providing the details of similar transformations documented with other metals so that the complementary reactivity/diversity of these transformations could be appreciated.</p>},
	keywords = {alpha-Oxo Gold Carbene, Anthranil, Gold-catalysis, Internal Redox Cyclization, Isatogen},
	issn = {1527-8999},
	doi = {10.1002/tcr.202100111, Early Access Date = JUN 2021},
	author = {Dhote, Pawan S. and Halnor, Swapnil V. and Ramana, Chepuri V.}
}
@article {48677,
	title = {Rh-catalyzed C-H functionalization of the (Pyrazol-5-yl)pyridine core of GBT-440},
	journal = {Synthesis-Stuttgart},
	volume = {55},
	year = {2023},
	month = {NOV },
	pages = {3600-3609},
	type = {Article},
	abstract = {<p>
	The Rh-catalyzed cross dehydrogenative coupling (CDC)/alkylation of the pyrazolylpyridine unit of GBT-440 proceeded smoothly under ambient conditions and selectively on the pyrazole unit while directed by the pyridine. The scope of these reactions was established by employing simple as well as conjugated olefins for CDC and various diazo esters and the TIPS-EBX reagent for alkylation. At the outset, a focused small molecule library around the bis-heterocyclic core of GBT440 was developed via C-H functionalization.</p>
},
	keywords = {C-H activation, cross dehydrogenative coupling, diazo ester, GBT-440, Rh catalysis, TIPS-EBX},
	issn = {0039-7881},
	doi = {10.1055/a-2116-6734},
	author = {Kalshetti, Rupali G. and Halnor, Swapnil V. and Ramana, Chepuri V.}
}
