@article { ISI:000318917000003,
	title = {Proline catalyzed sequential alpha-aminooxylation or -amination/reductive cyclization of o-nitrohydrocinnamaldehydes: a high yield synthesis of chiral 3-substituted tetrahydroquinolines},
	journal = {Organic \& Biomolecular Chemistry},
	volume = {11},
	number = {22},
	year = {2013},
	month = {APR},
	pages = {3608-3611},
	publisher = {ROYAL SOC CHEMISTRY},
	address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND},
	abstract = {<p>A new sequential organocatalytic method for the synthesis of chiral 3-substituted (X = OH, NH2) tetrahydroquinoline derivatives (THQs) [ee up to 99\%, yield up to 87\%] based on alpha-aminooxylation or -amination followed by reductive cyclization of o-nitrohydrocinnamaldehydes has been described. This methodology has been efficiently demonstrated in the synthesis of two important bioactive molecules namely (-)-sumanirole (96\% ee) and 1-[(S)-3-(dimethylamino)-3,4-dihydro-6,7-dimethoxy-quinolin-1(2H)-yl]- propanone (92\% ee).</p>},
	issn = {1477-0520},
	doi = {10.1039/c3ob40320c},
	author = {Rawat, Varun and Kumar, B. Senthil and Sudalai, Arumugam}
}
@article { ISI:000349934600083,
	title = {Proline-catalyzed sequential syn-mannich and [4+1]-annulation cascade reactions to form densely functionalized pyrrolidines},
	journal = {Journal of Organic Chemistry},
	volume = {80},
	number = {3},
	year = {2015},
	month = {FEB},
	pages = {2024-2031},
	publisher = {AMER CHEMICAL SOC},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>A highly efficient one-pot [4 + 1]-annulation process for the asymmetric synthesis of densely functionalized pyrrolidine derivatives is described. The in situ generated syn-Mannich adduct obtained via proline catalysis acts as a four-atom component, and Coreys sulfur ylide or ethyl bromoacetate acts as a one-atom carbon source to construct pyrrolidine units in a highly enantio- and diastereoselective manner.</p>},
	issn = {0022-3263},
	doi = {10.1021/jo5028886},
	author = {Aher, Ravindra D. and Kumar, B. Senthil and Sudalai, Arumugam}
}
