@article { ISI:000378303400056,
	title = {Nucleophilic nitration of arynes by sodium nitrite and its multicomponent reaction leading to double-functionalized arenes},
	journal = {Organic Letters},
	volume = {18},
	number = {12},
	year = {2016},
	month = {JUN},
	pages = {3010-3013},
	publisher = {AMER CHEMICAL SOC},
	address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA},
	abstract = {<p>An unusual nucleophilic nitration of arynes by NaNO2 in the presence of water has been developed, and the concept was further demonstrated to accomplish a double functionalization of arynes using a multicomponent reaction protocol to synthesize pharmaceutically important (2-nitrophenyl)methanol derivatives. Such substitution ortho to -NO2 is difficult by other means. The reaction conditions are mild and avoid the use of strong acids, expensive transition metal catalysts, and additives.</p>},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.6b01384},
	author = {Dhokale, Ranjeet A. and Mhaske, Santosh B.}
}
@article {48343,
	title = {Nickel-catalyzed direct synthesis of N-substituted indoles from amino alcohols and alcohols},
	journal = {Organic Letters},
	volume = {24},
	year = {2022},
	month = {DEC},
	pages = {9054-9059},
	type = {Article},
	abstract = {<p>
	A one-pot cascade approach for the synthesis of N substituted indoles from amino alcohols and alcohols under additive and base-free conditions with the liberation of water as the only stoichiometric byproduct is reported. The commercially available bench-stable Ni(OTf)2 salt in combination with 1,2-bis(dicyclohexylphosphino)ethane (dcype) is very effective for this unprecedented catalytic transformation. A broad range of substrates including aromatic and aliphatic primary alcohols, cyclic and acyclic secondary alcohols, and various substituted 2-aminophenyl ethyl alcohols are employed in the reaction conditions to provide a diverse range of N-alkylated indoles. Mechanistic studies revealed that the reaction proceeds through tandem N-alkylation via hydrogen autotransfer followed by the cyclization of N-alkylated alcohol intermediate.</p>
},
	issn = {1523-7060},
	doi = {10.1021/acs.orglett.2c03617},
	author = {Yadav, Vinita and Jagtap, Sayali G. and Balaraman, Ekambaram and Mhaske, Santosh B.}
}
