@article { ISI:000246320900026,
	title = {Hexamethyldisilazane-iodine induced intramolecular dehydrative cyclization of diamides: a general access to natural and unnatural quinazolinones},
	journal = {Tetrahedron Letters},
	volume = {48},
	number = {18},
	year = {2007},
	month = {APR},
	pages = {3243-3246},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A simple and efficient general approach to various quinazolinone scaffolds, including peptidomimetic examples, has been demonstrated by employing HMDS/I-2 for the intramolecular dehydrative cyclization of diamides. The protecting groups -Boc, -Fmoc and -Cbz tolerated the present reaction conditions and we did not observe any racemization. The present protocol has also been used as a key step for the efficient four-step syntheses of the naturally occurring quinazolinones, sclerotigenin, (-)-circumdatin-F and (-)-fumiquinazoline-F. (c) 2007 Elsevier Ltd. All rights reserved.</p>},
	keywords = {diamides, HMDS/I-2, intramolecular dehydrative cyclizations, natural and unnatural quinazolinones, synthesis},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2007.03.032},
	author = {Kshirsagar, Umesh A. and Mhaske, Santosh B. and N. P. Argade}
}
@article {46995,
	title = {Highly enantioselective synthesis of sitagliptin},
	journal = {Asian Journal of Organic Chemistry},
	volume = {9},
	year = {2020},
	month = {FEB},
	pages = {189-191},
	type = {Article},
	abstract = {<p>A highly enantioselective synthesis of sitagliptin, a potent DPP-4 inhibitor, is reported. Explicitly identified chiral FerroLANE ligands in the presence of rhodium catalyze the asymmetric hydrogenation of an enamine to yield sitagliptin with excellent enantioselectivity (98\% ee). The process was scaled up to 5 g and the final product was isolated as a phosphate salt with \&gt;99\% ee.</p>
},
	keywords = {asymmetric hydrogenation, catalysis, FerroLANE ligands, Rhodium, sitagliptin},
	issn = {2193-5807},
	doi = {10.1002/ajoc.201900709, Early Access Date = JAN 2020},
	author = {Khopade, V. Kishor and Sen, Anirban and Birajdar, Rajkumar S. and Paulbudhe, Uday P. and Kavale, Dattatry S. and Shinde, Prashant S. and Mhaske, Santosh B. and Chikkali, Samir H.}
}
