@article { ISI:000236437400010,
	title = {Haval-Argade contrathermodynamic rearrangement of alkylidenesuccinimides to alkylmaleimides via the corresponding isoimides: a general approach to alkyl and dialkyl substituted maleimides},
	journal = {Tetrahedron},
	volume = {62},
	number = {15},
	year = {2006},
	month = {APR},
	pages = {3557-3563},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A simple and efficient access to alkyl and dialkyl substituted maleimides has been demonstrated via the new contrathermodynamic rearrangement of (E)-alkylidenesuccinimides to alkylinaleimides. The (E)-alkylidenesuccinimides obtained from the Wittig-condensation of N-arylmaleimide with aliphatic aldehydes oil regioselective hydrolysis furnished the corresponding (E)-alkylidenesuccinanilic acids in 95-98\% yields. The beta-alkylidenesuccinanilic acids oil treatment with cyanuric chloride in the presence of triethylamine gave the corresponding beta-alkylisomaleimides in 78-80\% yields via the beta-alkylideneisosuccinimides with the exocyclic to endocyclic carbon-carbon double bond migration. The kinetically controlled products alkylisomaleimides in refluxing acetic acid furnished the thermodynamically controlled alkylinaleimides in 98\% yield. The Wittig condensation of alkyl substituted isomaleimides/maleimides with aliphatic aldehydes gave the desired dialkyl substituted maleimides in high yields. A conversion of alpha-methylenesuccinanilic acids to alpha-methylisomaleimides has also been described, with 90\% yield. (c) 2006 Elsevier Ltd. All rights reserved.</p>},
	keywords = {alkyl and dialkylmaleimides, contrathermodynamic rearrangement, isomaleimides, maleimides, wittig coupling},
	issn = {0040-4020},
	doi = {10.1016/j.tet.2006.01.091},
	author = {Haval, Kishan P. and N. P. Argade}
}
@article { ISI:000246320900026,
	title = {Hexamethyldisilazane-iodine induced intramolecular dehydrative cyclization of diamides: a general access to natural and unnatural quinazolinones},
	journal = {Tetrahedron Letters},
	volume = {48},
	number = {18},
	year = {2007},
	month = {APR},
	pages = {3243-3246},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	type = {Article},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A simple and efficient general approach to various quinazolinone scaffolds, including peptidomimetic examples, has been demonstrated by employing HMDS/I-2 for the intramolecular dehydrative cyclization of diamides. The protecting groups -Boc, -Fmoc and -Cbz tolerated the present reaction conditions and we did not observe any racemization. The present protocol has also been used as a key step for the efficient four-step syntheses of the naturally occurring quinazolinones, sclerotigenin, (-)-circumdatin-F and (-)-fumiquinazoline-F. (c) 2007 Elsevier Ltd. All rights reserved.</p>},
	keywords = {diamides, HMDS/I-2, intramolecular dehydrative cyclizations, natural and unnatural quinazolinones, synthesis},
	issn = {0040-4039},
	doi = {10.1016/j.tetlet.2007.03.032},
	author = {Kshirsagar, Umesh A. and Mhaske, Santosh B. and N. P. Argade}
}
