@article {49412,
	title = {Hypervalent-iodine-mediated base-free oxidative olefination of benzylic amines to access α,β-unsaturated ketones},
	journal = {Synlett},
	year = {2024},
	month = {AUG},
	type = {Article; Early Access},
	abstract = {<p>
	We report a one-pot base-free protocol for the oxidative olefination of benzylic amines promoted by a hypervalent iodine reagent for the synthesis of alpha,beta-unsaturated ketones. Mechanistically, (diacetoxyiodo)benzene oxidizes the benzylic amine to the corresponding imine, which, on reaction with a phenacyl(triphenyl)phosphonium bromide salt and an in situ generated acetoxy anion leads to an alpha,beta-unsaturated ketone. A wide range of alpha,beta-unsaturated ketones were easily accessed through direct oxidative olefination of substituted benzylic amines in good to excellent yields and with high E -selectivity.</p>
},
	keywords = {benzylic amines, enones, hypervalent iodine, olefination, Oxidation},
	issn = {0936-5214},
	doi = {10.1055/s-0043-1775392},
	author = {Rupanawar, Bapurao D. and Bansode, Ajay H. and Suryavanshi, Gurunath}
}
