@article {44199, title = {First total synthesis of (+/-)-rhodoconferimide}, journal = {Synthesis-Stuttgart}, volume = {50}, year = {2018}, month = {FEB}, pages = {658-662}, type = {Article}, abstract = {

Starting from vanillin and dimethyl maleate, a concise and efficient racemic total synthesis of the potent antioxidant marine natural product (+/-)-rhodoconferimide has been carried out via the Wittig reaction, catalytic hydrogenation, selective brominations, and imide formation. An appropriate regioselective double bromination of the aromatic ring was a key step in the synthesis.

}, keywords = {(+/-)-rhodoconferimide, Antioxidants, Bromination, Natural products, Total synthesis, Vanillin}, issn = {0039-7881}, doi = {10.1055/s-0036-1590944}, author = {Pandhade, Kailas R. and N. P. Argade} }