@article { ISI:000339012400004, title = {Biocatalyst mediated functionalization of salannin, an insecticidal limonoid}, journal = {RSC Advances}, volume = {4}, number = {53}, year = {2014}, month = {JUN}, pages = {27661-27664}, publisher = {ROYAL SOC CHEMISTRY}, type = {Article}, address = {THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND}, abstract = {

Transformation of salannin, an insecticidal C-seco limonoid was investigated using a fungal system, Cunninghamella echinulata. Salannin was efficiently converted into two metabolites, where the C-17 furan moiety was transformed into gamma-hydroxybutenolide (salanninolide) and N-(2-hydroxyethyl)-alpha,beta-unsaturated-gamma-lactam (salanninactam) analogues. Present studies have indicated salanninolide to be a metabolite in the C-seco limonoid biosynthetic pathway.

}, issn = {2046-2069}, doi = {10.1039/c4ra04652h}, author = {Haldar, Saikat and Kolet, Swati P. and Dandekar, Devdutta S. and Kale, Balaji S. and Gonnade, Rajesh G. and Thulasiram, Hirekodathakallu V.} }