@article { ISI:000359962900040, title = {Glycine-linked nucleoside-beta-amino acids: polyamide analogues of nucleic acids}, journal = {Bioconjugate Chemistry}, volume = {26}, number = {8}, year = {2015}, month = {AUG}, pages = {1737-1742}, publisher = {AMER CHEMICAL SOC}, address = {1155 16TH ST, NW, WASHINGTON, DC 20036 USA}, abstract = {

3{\textquoteright}-5{\textquoteright}-Deoxyribose-sugar-phoshate backbone in DNA is completely replaced by 2{\textquoteright}-deoxyribonucleoside-based beta-amino acids interlinked by glycine to create uncharged polyamide DNA with 3{\textquoteright}-5{\textquoteright}-directionality. These oligomers as conjugates of alpha-amino acids and nucleoside-beta-amino acids bind strongly and sequence-specifically only to the antiparallel complementary RNA and DNA.

}, issn = {1043-1802}, doi = {10.1021/acs.bioconjchem.5b00296}, author = {Banerjee, Anjan and Seema Bagmare and Varada, Manojkumar and Kumar, Vaijayanti A.} }